If you want to get to Galaxidi setting off from Southern Greece you have to follow the National Route which connects Thessaloniki with Lamia. After Thermopyles, at the 300th kilometer, there is an intersection –you have to direct towards Amfissa, continue to Nafpaktos and then Antirion.
If you set off from Athens you have to follow the National Route which connects Athens with Lamia. When you arrive to the junction of Kastro, you have to turn towards Orchomenos and then continue to Livadia, Arachova, Delphi, Itea and finally Galaxidi.
If you wish to set off from Western Greece you should follow the itinerary Nafpaktos- Itea- Galaxidi. If you drive from Peloponnese, after passing from the Bridge that connects Rion with Antirrion you reach to Nafpaktos.